In our collection, even though SOX11 was silenced in all circumstances displaying methylation, a vast assortment of samples, from regular cells to lymphoid neoplasms (Figure 2d), were being also silenced in spite of an unmethylated status of the SOX11 promoter
To elucidate whether DNA methylation correlates with SOX11 gene transcription, we quantified the methylation standing of six CpGs in the promoter area of SOX11 utilizing bisulfite pyrosequencing in the similar…