Decreased suppression of foods ingestion in response to exogenous leptin in HFD-fed adip-crePTP1B2/two mice indicates that they ended up far more leptin resistant than their HFD-fed controls
Diminished in vivo insulin signaling in subcutaneous white adipose tissue from HFD-fed adip-crePTP1B2/two mice. A: Subcutaneous white adipose tissue immunoblots of insulin signaling elements in chow- and HFD-fed fl/fl and…