ICs in these ovaries expressed Argos, an antagonist of EGF (Figure S6) that is secreted from EGFR signaleceiving cells into the extracellular matrix and sequester EGF ligands, thus attenuating EGFR signaling
Be aware that spitz, a gene encoding a main EGF ligand, displays a equivalent ubiquitous expression sample . (Ep9) LL3 wing imaginal discs stained for GFP and di-phosphorylated ERK (dpERK).…