Product Name: AZ 10417808
Subtitle: Caspase-3 inhibitor,selective non-peptide
Biological Activity: Biological Activity of AZ 10417808Selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH
SMLES:
CAS NO: 129830-38-2
Standard In CHIKey: RAD51 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H13Cl2N5O4
M.Wt: 434.23
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/362
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide