Product Name: AZD6482
Subtitle: PI3Kβ inhibitor,potent and selective
Biological Activity: Biological Activity of AZD6482Potent and selective inhibitor of PI 3-kinase β (PI 3-Kβ) (IC50 values are 0.69, 13.6, 47.8 and 136 nM for PI 3-Kβ, PI 3-Kδ, PI 3-Kγ and PI 3-Kα, respectively). Selectively inhibits in vivo growt
SMLES:
CAS NO: 195514-80-8
Standard In CHIKey: Nucleoside Antimetabolite_Analog inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H24N4O4
M.Wt: 408.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/676
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 10 mM in 1eq. HCl
Storage: Store at -20℃
Purity: >98%
Chemical Name: (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid