Product Name: CP-724714
Subtitle: HER2 inhibitor,potent and selective
Biological Activity: Biological Activity of CP-724714Description CP-724714 is an inhibitor of erbB2 and EGFR kinases with IC50 values of 10±3 nM and 6,400±2,100 nM, respectively. Targets erbB2 EGFR IC50 10±3 nM 6,400±2,100 nM
SMLES: CC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C=CCNC(=O)COC)C
CAS NO: 119413-54-6
Standard In CHIKey: Porcupine inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H27N5O3
M.Wt: 469.53
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/1084
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide