Product Name: GSK2126458
Subtitle: PI3K/mTOR inhibitor
Biological Activity: Biological Activity of GSK2126458Description GSK2126458 is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki values of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM, respectively. Targets p110α p110δ p110γ p110β mT
SMLES: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
CAS NO: 1365888-06-7
Standard In CHIKey: 5-HT Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H17F2N5O3S
M.Wt: 505.5
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/901
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide