Product Name: JNJ-26854165 (Serdemetan)
Subtitle: P53 activator, blocking Mdm2-p53 interaction
Biological Activity: Biological Activity of JNJ-26854165 (Serdemetan)Description JNJ-26854165 (Serdemetan) is an antagonist of HDM2 ubiquitin ligase and also inducer of early apoptosis in p53 wild-type cells, Targets HDM2 Mdm2 IC50
SMLES: C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4
CAS NO: 923287-50-7
Standard In CHIKey: HDAC inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H20N4
M.Wt: 328.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/272
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-N-[2-(1H-indol-3-yl)ethyl]-4-N-pyridin-4-ylbenzene-1,4-diamine