Product Name: JNK-IN-8
Subtitle: JNK inhibitor, selective and irreversible
Biological Activity: Biological Activity of JNK-IN-8Description JNK-IN-8 is a selective and irreversible type 2 inhibitor of JNK with IC50 value of 4.67 nM, 18.7 nM and 980 pM for JNK1, JNK2 and JNK3, respectively. Targets JNK1 JNK2 JNK3 IC50 4.67 nM 18.
SMLES: CC1=C(C=CC(=C1)NC(=O)C2=CC(=CC=C2)NC(=O)C=CCN(C)C)NC3=NC=CC(=N3)C4=CN=CC=C4
CAS NO: 1181770-72-8
Standard In CHIKey: CMV inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C29H29N7O2
M.Wt: 507.59
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/276
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide