Product Name: LY2940680
Subtitle: Hedgehog/SMO antagonist,inhibits Hh signaling
Biological Activity: Biological Activity of LY2940680Description LY2940680 is a potent inhibitor of Smoothened (Smo) receptor and Hedgehog (Hh) signaling. Targets Smoothened IC50
SMLES: CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F
CAS NO: 1426802-50-7
Standard In CHIKey: Tyrosinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H24F4N6O
M.Wt: 512.5
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/2/871
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-fluoro-N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-2-(trifluoromethyl)benzamide