Product Name: Lactacystin
Subtitle: Proteasome inhibitor
Biological Activity: Biological Activity of Lactacystin A cell-permeable, potent and selective proteasome inhibitor. A Streptomyces metabolite that is thought to bind irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S prote
SMLES: CC(C)C[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O
CAS NO: 1129403-56-0
Standard In CHIKey: KZZNIEYFCKAJPQ-VRKAVTRVSA-NNotch inhibitors
Standard InChI: InChI=1S/C16H26N2O7S/c1-7(2)5-11(20)16(12(21)8(3)13(22)18-16)15(25)26-6-10(14(23)24)17-9(4)19/h7-8,10-12,20-21H,5-6H2,1-4H3,(H,17,19)(H,18,22)(H,23,24)/t8-,10+,11+,12+,16-/m1/s1
Typrof Compound: Miscellaneous
Appearance: Powder
Formula: C15H24N2O7S
M.Wt: 376.43
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/3/1360
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in water
Storage: Desiccate at -20℃
Purity: > 95%
Chemical Name: (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxy-N-acetyl-L-cysteine thioester