Product Name: MEK162 (ARRY-162, ARRY-438162)
Subtitle: MEK1/2 inhibitor,potent and selective
Biological Activity: Biological Activity of MEK162 (ARRY-162, ARRY-438162)Description MEK162 is a potent inhibitor of MEK1/2 with IC50 value of 12 nM. Targets MEK1 MEK2 IC50 12 nM 12 nM
SMLES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO
CAS NO: 187235-37-6
Standard In CHIKey: Protease_Inhibitor_Cocktail_mini-Tablet inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H15BrF2N4O3
M.Wt: 441.23
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/165
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: Binimetinib