Product Name: Mdivi 1
Subtitle: Selective DRP1/Dnm1 inhibitor, cell-permeable
Biological Activity: Biological Activity of Mdivi 1Selective inhibitor of Dnm1 GTPase (IC50 = 1 – 10 μM); attenuates Dnm1- and Drp1-mediated mitochondrial division. Inhibits mitochondrial outer membrane permeabilization (MOMP) and attenuates apoptosis.
SMLES: COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl
CAS NO: 1187594-09-7
Standard In CHIKey: MicroRNA inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C15H10Cl2N2O2S
M.Wt: 353.22
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/439
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone