Product Name: Nutlin-3b
Subtitle: MDM2/p53 inhibitor
Biological Activity: Biological Activity of Nutlin-3bDescription Nutlin-3b is an inhibitor of p53-MDM2 interaction with IC50 value of 13.6 µM. Targets p53-MDM2 interaction IC50 13.6 µM
SMLES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
CAS NO: 923564-51-6
Standard In CHIKey: Apoptosis inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C30H30Cl2N4O4
M.Wt: 581.49
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/250/3/944
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one