Product Name: Obatoclax mesylate (GX15-070)
Subtitle: Potent Bcl-2 inhibitor
Biological Activity: Biological Activity of Obatoclax mesylate (GX15-070)Obatoclax (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM, can assist in overcoming MCL-1 mediated resistance to apoptosis. Targets Bcl-2 IC50 0.22 μM (Ki)
SMLES: CC1=CC(=C(N1)C=C2C(=CC(=C3C=C4C=CC=CC4=N3)N2)OC)C.CS(=O)(=O)O
CAS NO: 1029044-16-3
Standard In CHIKey: DNA Stain inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H19N3O.CH4O3S
M.Wt: 413.5
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/238
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (2Z)-2-[(5Z)-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-4-methoxypyrrol-2-ylidene]indole;methanesulfonic acid