Product Name: PKI-402
Subtitle: PI3K inhibitor,selective, reversible and ATP-competitive
Biological Activity: Biological Activity of PKI-402Description PKI-402 is a potent dual inhibitor of PI3K/mTOR with IC50 values of 2 nM/7 nM/16 nM/14 nM and 3 nM for PI3Kα/β/γ/δ and mTOR, respectively. Targets PI3Kα mTOR PI3Kβ PI3Kδ PI3Kγ IC50 2 nM 3 nM 7
SMLES: CCN1C2=C(C(=NC(=N2)C3=CC=C(C=C3)NC(=O)NC4=CC=C(C=C4)C(=O)N5CCN(CC5)C)N6CCOCC6)N=N1
CAS NO: 1257044-40-8
Standard In CHIKey: MicroRNA inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C29H34N10O3
M.Wt: 570.65
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/879
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: 1-[4-(3-ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea