Product Name: PP242
Subtitle: MTOR inhibitor, selective and ATP-competitive
Biological Activity: Biological Activity of PP242ATP-competitive mTORC1/mTORC2 inhibitor (IC50 = 8 nM). Displays selectivity for mTOR over other PI 3K family kinases (IC50 values are 0.102, 0.408, 1.27, 1.96 and 2.2 μM for p110γ, DNA-PK, p110δ, p110α and p
SMLES: CC(C)N1C2=C(C(=C3C=C4C=C(C=CC4=N3)O)N1)C(=NC=N2)N
CAS NO: 923564-51-6
Standard In CHIKey: Epigenetics inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H16N6O
M.Wt: 308.35
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/820
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol