Product Name: PRIMA-1
Subtitle: BAX inhibitor
Biological Activity: Biological Activity of PRIMA-1Selectively restores mutant p53 activity in tumor cells via activation of Bax and PUMA. Induces apoptosis and inhibits growth of human tumors with mutant p53.
SMLES: C1CN2CCC1C(=O)C2(CO)CO
CAS NO: 198821-22-6
Standard In CHIKey: RFBVBRVVOPAAFS-UHFFFAOYSA-NCaSR inhibitors
Standard InChI: InChI=1S/C9H15NO3/c11-5-9(6-12)8(13)7-1-3-10(9)4-2-7/h7,11-12H,1-6H2
Typrof Compound:
Appearance:
Formula: C9H15NO3
M.Wt: 185.22
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/518
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2,2-Bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one