Product Name: Pexmetinib (ARRY-614)
Subtitle: dual inhibitor of p38 MAPK and Tie2/Tek receptor tyrosine kinase
Biological Activity:
SMLES: CC1=CC=C(N2C(N/C(O)=N/CC3=CC(F)=CC=C3OC4=CC=C5C(C=NN5CCO)=C4)=CC(C(C)(C)C)=N2)C=C1
CAS NO: 1256580-46-7
Standard In CHIKey: Dynamin inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C31H33FN6O3
M.Wt: 556.63
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/680
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: (Z)-N-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-N-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)carbamimidic acid