Product Name: RG7112
Subtitle: MDM2 inhibitor, first clinical
Biological Activity: Biological Activity of RG7112Description RG7112 is the first clinical small-molecule inhibitor of MDM2. Targets MDM2 IC50
SMLES: CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl
CAS NO: 1403254-99-8
Standard In CHIKey: Cell Cycle_DNA Damage inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C38H48Cl2N4O4S
M.Wt: 727.78
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/169
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone