Product Name: RS 127445
Subtitle: 5-HT2B receptor antagonist,high affinity
Biological Activity: Biological Activity of RS 127445Description RS 127445 is a high affinity antagonist of 5-HT2B receptor with pKi value of 9.5. Targets 5-HT2B receptor IC50 9.5 (pKi)
SMLES: CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.Cl
CAS NO: 57-85-2
Standard In CHIKey: ZZZQXCUPAJFVBN-UHFFFAOYSA-NULK inhibitors
Standard InChI: InChI=1S/C17H16FN3/c1-10(2)15-9-16(21-17(19)20-15)13-7-8-14(18)12-6-4-3-5-11(12)13/h3-10H,1-2H3,(H2,19,20,21)
Typrof Compound:
Appearance:
Formula: C17H17ClFN3
M.Wt: 317.79
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/268/1/117
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine