Product Name: SMI-4a
Subtitle: Potent Pim inhibitor
Biological Activity: Biological Activity of SMI-4aSelective, ATP-competitive Pim kinase inhibitor (IC50 values are 24 and 100 nM for Pim-1 and Pim-2 respectively). Displays selectivity over a panel of ~50 other kinases tested. Exhibits cytotoxicity in PC3 prostate carcinoma c
SMLES: C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2
CAS NO: 1206801-37-7
Standard In CHIKey: Estrogen Receptor_ERR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C11H6F3NO2S
M.Wt: 273.23
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/809
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: (5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione