Product Name: Sabutoclax
Subtitle: pan-Bcl-2 inhibitor
Biological Activity: Biological Activity of SabutoclaxDescription Sabutoclax(BI-97C1) is a inhibitor of Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 values of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively. Targets Bcl-xL Bcl-2 Mcl-1 Bfl-1 IC50 0.31 μM 0
SMLES: CC1=C(C(=C2C=C(C(=C(C2=C1)C(=O)NCC(C)C3=CC=CC=C3)O)O)O)C4=C(C=C5C(=C4O)C=C(C(=C5C(=O)NCC(C)C6=CC=CC=C6)O)O)C
CAS NO: 266359-83-5
Standard In CHIKey: DNA_RNA Synthesis inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C42H40N2O8
M.Wt: 700.78
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/253
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2,3,5-trihydroxy-7-methyl-N-[(2R)-2-phenylpropyl]-6-[1,6,7-trihydroxy-3-methyl-5-[[(2R)-2-phenylpropyl]carbamoyl]naphthalen-2-yl]naphthalene-1-carboxamide