Product Name: Torin 1
Subtitle: MTOR inhibitor,potent and selective
Biological Activity: Biological Activity of Torin 1Potent and selective mTOR inhibitor (IC50 = 2 – 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34. Induces autophagy in HeLa cells.
SMLES: CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F
CAS NO: 243984-11-4
Standard In CHIKey: Gap Junction Protein inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C35H28F3N5O2
M.Wt: 607.64
General Tips: for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/795
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 1 mM in DMSO with gentle warming
Storage: Store at +4℃
Purity: >98%
Chemical Name: 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one