Product Name: Cyclo (-RGDfK)Subtitle: Inhibitor of αvβ3 integrinBiological Activity: Biological Activity of Cyclo (-RGDfK)Description Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin. Targets Integrin IC50SMLES: C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)OCAS…
Product Name: IOX2(Glycine)Subtitle: HIF-1α prolyl hydroxylase-2 (PHD2) inhibitorBiological Activity: Biological Activity of IOX2(Glycine)Potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over…
Product Name: FG-4592 (ASP1517)Subtitle: HIF prolyl-hydroxylase inhibitorBiological Activity: Biological Activity of FG-4592 (ASP1517)Description FG-4592 is an inhibitor of HIF α prolyl hydroxylase. Targets HIF α prolyl hydroxylase IC50SMLES: CC1=NC(=C(C2=C1C=C(C=C2)OC3=CC=CC=C3)O)C(=O)NCC(=O)OCAS NO:…
Product Name: ZaurategrastSubtitle: Integrin inhibitorBiological Activity: SMLES: C1CCC2(CC1)C(=C(C2=O)Br)NC(CC3=CC=C(C=C3)NC4=NC=CC5=C4C=NC=C5)C(=O)OCAS NO: 119413-54-6Standard In CHIKey: EBI2_GPR183 inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H25BrN4O3M.Wt: 521.42General Tips: For obtaining a higher solubility , please warm…
Product Name: FirategrastSubtitle: α4β1/α4β7 integrin antagonistBiological Activity: Biological Activity of FirategrastDescription Firategrast is an orally bioavailable antagonist of alpha4 beta1/alpha4 beta7 integrin. Targets α4β1/α4β7 integrin IC50SMLES: CCOCC1=CC(=C(C(=C1)OC)C2=CC=C(C=C2)CC(C(=O)O)NC(=O)C3=C(C=CC=C3F)F)OCCAS NO: 478182-28-4Standard In…
Product Name: CGI-1746Subtitle: Btk inhibitorBiological Activity: Biological Activity of CGI-1746Description CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC50 value of 1.9 nM. Targets Btk…
Product Name: AVL-292Subtitle: Btk inhibitorBiological Activity: Biological Activity of AVL-292Description AVL-292 is a highly selective, orally active small-molecule inhibitor of Btk with IC50 value of 0.5 nM. Targets Btk IC50…
Product Name: PCI-32765 (Ibrutinib)Subtitle: Brutons tyrosine kinase (BTK) inhibitorBiological Activity: Biological Activity of PCI-32765 (Ibrutinib)Description Ibrutinib is a potent and highly selective inhibitor of Btk with IC50 of 0.5 nM,…
Product Name: PRIMA-1Subtitle: BAX inhibitorBiological Activity: Biological Activity of PRIMA-1Selectively restores mutant p53 activity in tumor cells via activation of Bax and PUMA. Induces apoptosis and inhibits growth of human…
Product Name: Pifithrin-μSubtitle: Inhibitor of p53 binding and anti-apoptoticBiological Activity: Biological Activity of Pifithrin-μInhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. Displays no…