Product Name: NSC 687852 (b-AP15)Subtitle: 19S regulatory particle InhibitorBiological Activity: Biological Activity of NSC 687852 (b-AP15)Inhibitor of 19S regulatory particle associated deubiquitinating enzymes (DUBs), UCHL5 and USP14. Shows minimal inhibition…
Product Name: Mitomycin CSubtitle: Inhibits DNA synthesis,antibiotic and antitumor agentBiological Activity: Biological Activity of Mitomycin CAntibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis.…
Product Name: CHM 1Subtitle: Tubulin polymerization inhibitorBiological Activity: Biological Activity of CHM 1Inducer of apoptosis; displays potent antitumor ability in human hepatocellular carcinoma. Inhibits tubulin polymerization in vitro and in…
Product Name: C 75Subtitle: Fatty acid synthase (FAS) inhibitorBiological Activity: Biological Activity of C 75Synthetic inhibitor of fatty acid synthase (FASN); inhibits fatty acid synthesis in vitro and in vivo.…
Product Name: Actinomycin DSubtitle: RNA polymerase inhibitorBiological Activity: Biological Activity of Actinomycin DAnti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis.SMLES: CAS NO: 201410-53-9Standard In CHIKey: RJURFGZVJUQBHK-UHFFFAOYSA-NWee1…
Product Name: 2,3-DCPE hydrochlorideSubtitle: Bcl-XL protein expression downregulatorBiological Activity: SMLES: ClC1=CC=CC(OCCCNCCO)=C1Cl.ClCAS NO: 1243244-14-5Standard In CHIKey: QVEIRCZEBQRCTR-UHFFFAOYSA-OTopoisomerase inhibitorsStandard InChI: InChI=1S/C11H15Cl2NO2/c12-9-3-1-4-10(11(9)13)16-8-2-5-14-6-7-15/h1,3-4,14-15H,2,5-8H2/p+1Typrof Compound: Appearance: Formula: C11H15Cl2NO2.HClM.Wt: 300.61General Tips: For obtaining a higher solubility…
Product Name: R18Subtitle: 14.3.3 proteins AntagonistBiological Activity: Biological Activity of R18Antagonist of 14.3.3 proteins (KD ≈80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to…
Product Name: PETCMSubtitle: Caspase-3 activatorBiological Activity: Biological Activity of PETCMCaspase-3 activator. Acts via inhibition of the oncoprotein ProT, therefore stimulates apoptosome formation and subsequent caspase-3 activation in a cytochrome c-dependent…
Product Name: Ac-LEHD-AFCSubtitle: Fluorogenic caspase substrateBiological Activity: Biological Activity of Ac-LEHD-AFCFluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.SMLES: CAS NO: 1402836-58-1Standard In CHIKey: Sirtuin inhibitorsStandard InChI: Typrof Compound: Appearance:…
Product Name: IvachtinSubtitle: Caspase-3 inhibitorBiological Activity: SMLES: CC1=C2C(=C3C=C(C=CC3=N1)S(=O)(=O)N4CCOCC4)C(=O)N(C2=O)CCOC(=O)CCAS NO: 1186206-79-0Standard In CHIKey: ROCK inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C20H21N3O7SM.Wt: 447.46General Tips: For obtaining a higher solubility , please warm…