Product Name: 2-Methoxyestradiol (2-MeOE2)Subtitle: Apoptotic, antiproliferative and antiangiogenic agentBiological Activity: Biological Activity of 2-Methoxyestradiol (2-MeOE2)Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo; acts via an estrogen receptor-independent mechanism.…
Product Name: Apoptosis Activator 2Subtitle: Indoledione caspase activator, cell-permeableBiological Activity: Biological Activity of Apoptosis Activator 2Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9…
Product Name: Necrostatin 2 S enantiomerSubtitle: In vitro necroptosis inhibitorBiological Activity: SMLES: ClC1=CC=CC2=C1NC=C2C3C(N(C)C(N3)=O)=OCAS NO: 906805-42-3Standard In CHIKey: CRISPR_Cas9 inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C13H12ClN3O2M.Wt: 277.71General Tips: For obtaining a…
Product Name: Necrostatin 2 racemateSubtitle: In vitro necroptosis inhibitorBiological Activity: SMLES: ClC1=CC=CC2=C1NC=C2CC3NC(N(C)C3=O)=OCAS NO: 459868-92-9Standard In CHIKey: Checkpoint Kinase Chk) inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C13H12ClN3O2M.Wt: 277.71General Tips: For obtaining…
Product Name: YM-155 hydrochlorideSubtitle: Potent survivin inhibitorBiological Activity: Biological Activity of YM-155 hydrochlorideDescription YM-155 hydrochloride is a potent and small-molecule inhibitor of survivin with IC50 value of 0.54 nM. Targets…
Product Name: WEHI-539Subtitle: Bcl-xL inhibitor,potent and selectiveBiological Activity: Biological Activity of WEHI-539WEHI-539, has high affinity (subnanomolar) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival activity.…
Product Name: TrabectedinSubtitle: Antitumour agentBiological Activity: SMLES: CC1=C(C(=C2C3C4C5C6=C(C(N4C(C(N3C)CC2=C1)O)COC(=O)C7(CS5)C8=CC(=C(C=C8CCN7)O)OC)C9=C(C(=C6OC(=O)C)C)OCO9)O)OCCAS NO: 156161-89-6Standard In CHIKey: PKVRCIRHQMSYJX-MNJQDTOQSA-NAurora Kinase inhibitorsStandard InChI: InChI=1S/C39H43N3O11S/c1-16-9-20-10-22-37(46)42-23-13-50-38(47)39(21-12-25(48-5)24(44)11-19(21)7-8-40-39)14-54-36(30(42)29(41(22)4)26(20)31(45)32(16)49-6)28-27(23)35-34(51-15-52-35)17(2)33(28)53-18(3)43/h9,11-12,22-23,29-30,36-37,40,44-46H,7-8,10,13-15H2,Typrof Compound: Appearance: Formula: C39H43N3O11SM.Wt: 761.84General Tips: For obtaining a higher solubility , please…
Product Name: SPK-601Subtitle: Potent PC-PLC inhibitor,antimicrobial agentBiological Activity: SMLES: S=C(S)O1C2()C3()(CCC3)()1()C2CAS NO: 129453-61-8Standard In CHIKey: ATM_ATR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C11H15KOS2M.Wt: 266.47General Tips: For obtaining a higher solubility ,…
Product Name: SMIP004Subtitle: Apoptosis inducer;downreBiological Activity: SMLES: CCCCC1=CC(=C(C=C1)NC(=O)C)CCAS NO: 1234015-52-1Standard In CHIKey: APC inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C13H19NOM.Wt: 205.3General Tips: For obtaining a higher solubility , please warm…
Product Name: RG7388Subtitle: MDM2 antagonist, oral, selectiveBiological Activity: SMLES: CC(C)(C)CC1C(C(C(N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)FCAS NO: 1445379-92-9Standard In CHIKey: Antifolate inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C31H29Cl2F2N3O4M.Wt: 616.48General Tips: For obtaining a higher solubility ,…