Product Name: D609Subtitle: PC-PLC inhibitorBiological Activity: Biological Activity of D609Selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent. Suppresses LPS- and IFNγ-induced NO…
Product Name: BrassinolideSubtitle: Plant growth regulatorBiological Activity: SMLES: CC(C)(C)(O)(O)(C)1()CC2()3()COC(4()C(O)(O)C4(C)3()CC21C)=OCAS NO: 1643913-93-2Standard In CHIKey: IXVMHGVQKLDRKH-KNBKMWSGSA-NIAP inhibitorsStandard InChI: InChI=1S/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3/t15-,16-,17-,18+,19-,20-,21+,22-,23+,24+,25+,27+,28+/m0/s1Typrof Compound: Appearance: Formula: C28H48O6M.Wt: 480.68General Tips: For obtaining a higher solubility , please…
Product Name: BAM7Subtitle: BAX activator,direct and selectiveBiological Activity: Biological Activity of BAM7Bax activator (EC50 = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic…
Product Name: AT-101Subtitle: BH3-mimetic,gossypol enantiomerBiological Activity: Biological Activity of AT-101R-(-)-enantiomer of gossypol. Mimics the BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces…
Product Name: 3,3-DiindolylmethaneSubtitle: Anticancer and antineoplastic agentBiological Activity: Biological Activity of 3,3-DiindolylmethaneActivator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines. Antiproliferative and inducer of apoptosis;…
Product Name: AT-406 (SM-406)Subtitle: IAP inhibitorBiological Activity: SMLES: CAS NO: 1229705-06-9Standard In CHIKey: Bcl-2 Family inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C32H43N5O4M.Wt: 561.71General Tips: For obtaining a higher solubility ,…
Product Name: ABT-263 (Navitoclax)Subtitle: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-wBiological Activity: Biological Activity of ABT-263 (Navitoclax)ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with…
Product Name: Nutlin-3bSubtitle: MDM2/p53 inhibitorBiological Activity: Biological Activity of Nutlin-3bDescription Nutlin-3b is an inhibitor of p53-MDM2 interaction with IC50 value of 13.6 µM. Targets p53-MDM2 interaction IC50 13.6 µMSMLES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)ClCAS…
Product Name: Bendamustine HClSubtitle: Cytostatic agent for non-Hodgkin lymphomasBiological Activity: Biological Activity of Bendamustine HClCytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those…
Product Name: Apoptosis InhibitorSubtitle: Associate with caspase-3 inhibitionBiological Activity: Biological Activity of Apoptosis InhibitorDescription Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction. Targets Caspase IC50SMLES: CAS NO: 23007-85-4Standard In…