Product Name: Caspase-3/7 Inhibitor ISubtitle: Caspase-3/7 inhibitorBiological Activity: Biological Activity of Caspase-3/7 Inhibitor IA potent, cell-permeable, and specific, reversible inhibitor of caspase-3 (Ki = 60 nM) and caspase-7 (Ki =…
Product Name: Z-WEHD-FMKSubtitle: Caspase 5 inhibitor,potent,cell-permeable and irreversibleBiological Activity: Biological Activity of Z-WEHD-FMK A synthetic peptide that irreversibly inhibits caspase-5 and related caspase activity. Targets caspase-5 IC50SMLES: COC(=O)CCC(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)OCC4=CC=CC=C4CAS NO: 915087-33-1Standard…
Product Name: Z-VDVAD-FMKSubtitle: Caspase-2 inhibitorBiological Activity: Biological Activity of Z-VDVAD-FMKIrreversible caspase-2 inhibitor. Attenuates oxyhemoglobin-induced cleavage of PARP and apoptosis in endothelial cells. Targets Caspase-2 IC50SMLES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CC(=O)OC)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1CAS NO: 0Standard In CHIKey:…
Product Name: Z-DEVD-FMKSubtitle: Caspase-3 inhibitorBiological Activity: Biological Activity of Z-DEVD-FMK Z-DEVD-FMK is a cell-permeable, irreversible inhibitor of Caspase-3/CPP32. It is also an irreversible inhibitor of Caspase-6, Caspase-7, caspase-8, and Caspase-10.…
Product Name: Boc-D-FMKSubtitle: Pan-caspase inhibitorBiological Activity: Biological Activity of Boc-D-FMKDescription BOC-D-FMK is a Novel inhibitor of Caspase-3. Targets Caspase IC50SMLES: CAS NO: 1231930-82-7Standard In CHIKey: Rhinovirus HRV) inhibitorsStandard InChI: Typrof…
Product Name: Z-VAD-FMKSubtitle: Cell-permeable, irreversible pan-caspase inhibitorBiological Activity: Biological Activity of Z-VAD-FMKCell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 –…
Product Name: Q-VD-OPh hydrateSubtitle: Cell-permeable, irreversible pan-caspase inhibitorBiological Activity: Biological Activity of Q-VD-OPh hydrateQ-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm),…
Product Name: StreptozotocinSubtitle: Antibiotic and antitumor agentBiological Activity: Biological Activity of Streptozotocin Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic…
Product Name: PlumbaginSubtitle: Anticancer agentBiological Activity: Biological Activity of Plumbagin Anticancer agent. Induces G2/M cell cycle arrest and apoptosis in A549 cells through JNK-dependent p53 Ser15 phosphorylation; inhibits A549 and…
Product Name: PiplartineSubtitle: Inducer of cell-deathBiological Activity: Biological Activity of Piplartine Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and…