Product Name: Z-DEVD-FMKSubtitle: Caspase-3 inhibitorBiological Activity: Biological Activity of Z-DEVD-FMK Z-DEVD-FMK is a cell-permeable, irreversible inhibitor of Caspase-3/CPP32. It is also an irreversible inhibitor of Caspase-6, Caspase-7, caspase-8, and Caspase-10.…
Product Name: Boc-D-FMKSubtitle: Pan-caspase inhibitorBiological Activity: Biological Activity of Boc-D-FMKDescription BOC-D-FMK is a Novel inhibitor of Caspase-3. Targets Caspase IC50SMLES: CAS NO: 1231930-82-7Standard In CHIKey: Rhinovirus HRV) inhibitorsStandard InChI: Typrof…
Product Name: Z-VAD-FMKSubtitle: Cell-permeable, irreversible pan-caspase inhibitorBiological Activity: Biological Activity of Z-VAD-FMKCell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 –…
Product Name: Q-VD-OPh hydrateSubtitle: Cell-permeable, irreversible pan-caspase inhibitorBiological Activity: Biological Activity of Q-VD-OPh hydrateQ-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm),…
Product Name: StreptozotocinSubtitle: Antibiotic and antitumor agentBiological Activity: Biological Activity of Streptozotocin Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic…
Product Name: PlumbaginSubtitle: Anticancer agentBiological Activity: Biological Activity of Plumbagin Anticancer agent. Induces G2/M cell cycle arrest and apoptosis in A549 cells through JNK-dependent p53 Ser15 phosphorylation; inhibits A549 and…
Product Name: PiplartineSubtitle: Inducer of cell-deathBiological Activity: Biological Activity of Piplartine Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and…
Product Name: MatrineSubtitle: Alkaloid found in Sophora plantBiological Activity: Biological Activity of Matrine 1. Matrine has anticancer property, which include the inhibition of human osteosarcoma cells invasion and proliferation ,…
Product Name: Gambogic acidSubtitle: Caspase activator and apoptosis inducerBiological Activity: Biological Activity of Gambogic acid Apoptosis inducer in several tumor cell lines including T47D cells. Activates caspases (EC50 values are…
Product Name: EmbelinSubtitle: XIAP inhibitor,cell-permeableBiological Activity: Biological Activity of Embelin Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 μM in competition binding assay with Smac peptide);…