Name : Human FNDC1 Protein
Product Source :
Recombinant Human FNDC1 Protein is expressed from E.coli with His tag at the N-Terminus. It contains Ala33-Thr457.[Accession | Q4ZHG4-1]
Molecular Weight :
The protein has a predicted MW of 48.68 kDa. The protein migrates to 50-55 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in 20mM PB, 500mM NaCl, 10% Glycerol.
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Human FNDC1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. The purity of Human FNDC1 is greater than 95% as determined by SEC-HPLC.
Background :
Fibronectin type III domain‑containing protein 1 (FNDC1) is a protein that contains a major component of the structural domain of fibronectin.FNDC1 was highly upregulated and acted as an oncogene in BC. Therefore, targeting FNDC1 may be a potential strategy for the treatment of BC.
Synonyms :
FNDC2; KIAA1866; MEL4B3
References & Citations :
Yunwen C, Shanshan G, Zhifei B, Saijun C, Hua Y. The silencing of FNDC1 inhibits the tumorigenesis of breast cancer cells via modulation of the PI3K/Akt signaling pathway. Mol Med Rep. 2021 Jun;23(6):479. doi: 10.3892/mmr.2021.12118. Epub 2021 Apr 26. PMID: 33899120; PMCID: PMC8097762.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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