Name : Mouse IL-20 Protein
Product Source :
Recombinant Mouse IL-20 Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Leu25- Leu176.[Accession | Q9JKV9]
Molecular Weight :
The protein has a predicted MW of 19.5 kDa. Due to glycosylation, the protein migrates to 20-22 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in 20mM PB, 500mM NaCl (pH 8.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse IL-20 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse IL-20 is greater than 95% as determined by SEC-HPLC.
Background :
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC.
Synonyms :
IL-20; Cytokine Zcyto10; Zcyto10; IL10D; MGC96907
References & Citations :
(1) Ding WZ, Han GY, Jin HH, Zhan CF, Ji Y, Huang XL. Anti-IL-20 monoclonal antibody suppresses hepatocellular carcinoma progression. Oncol Lett. 2018 Nov;16(5):6156-6162. doi: 10.3892/ol.2018.9402. Epub 2018 Sep 5. PMID: 30333881; PMCID: PMC6176420.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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