Name : Human LEPR Protein
Product Source :
Recombinant Human LEPR Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Phe22-Asp839.[Accession | P48357-1]
Molecular Weight :
The protein has a predicted MW of 94.59 kDa. Due to glycosylation, the protein migrates to 120-150 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human LEPR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
Leptin receptor is a fundamental regulator in physiological functions of the regulation of food intake, energy homeostasis, immune function, and reproduction as well as on ovarian follicular cells on the placenta and lactating mammary glands.
Synonyms :
Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295; LEPR; DB; OBR
References & Citations :
Işık R, Özdil F. Leptin Receptor Gene Polymorphisms in Some Turkish Donkey Populations. J Equine Vet Sci. 2020 Jan;84:102823. doi: 10.1016/j.jevs.2019.102823. Epub 2019 Nov 16. PMID: 31864461.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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