Name : Mouse LOXL2 Protein
Product Source :
Recombinant Mouse LOXL2 Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gln26-Gln776.[Accession | P58022-1]
Molecular Weight :
The protein has a predicted MW of 85.53 kDa. Due to glycosylation, the protein migrates to 90-100 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 90% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse LOXL2 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.
Background :
Lysyl oxidase-like 2 (LOXL2) is a copper and lysine tyrosyl-quinone (LTQ)-dependent amine oxidase belonging to the lysyl oxidase (LOX) family, the canonical function of which is to catalyze the crosslinking of elastin and collagen in the extracellular matrix (ECM).
Synonyms :
Lysyl oxidase-like protein 2; LOR2
References & Citations :
Wen B, Xu LY, Li EM. LOXL2 in cancer: regulation, downstream effectors and novel roles. Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188435. doi: 10.1016/j.bbcan.2020.188435. Epub 2020 Sep 22. PMID: 32976981.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
CNTF Protein
LSECtin/CLEC4G Protein
Popular categories:
Frizzled-10
Carbonic Anhydrase 5A (CA5A)