Name : PE-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein

Product Source :
Recombinant PE-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GVYDGREHTV peptide.[Accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&GVYDGREHTV]

Molecular Weight :

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :

Formulation :
Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4).

Reconstitution :

Storage and Stability :
Valid for 6 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :

Background :
Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene.The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens. The Human HLA-A*0201 MAGE-A4 (GVYDGREHTV) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and GVYDGREHTV peptide of the MAGE-A4.

Synonyms :
HLA0201; MHC I; MAGE-A4; CT1.4; MAGE4A; MAGE4B; MAGE-X2; member 4

References & Citations :
(1)Kageyama S , Ikeda H , Miyahara Y , et al. Adoptive Transfer of MAGE-A4 T-cell Receptor Gene-Transduced Lymphocytes in Patients with Recurrent Esophageal Cancer[J]. Clinical Cancer Research, 2015, 21(10):2268.

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