Name : PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein

Product Source :
Recombinant PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide.[Accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&KVLEYVIKV]

Molecular Weight :

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :

Formulation :
Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4).

Reconstitution :

Storage and Stability :
Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :

Background :
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.

Synonyms :
MAGE-A1; MAGE A1; CT1.1; MAGE-1 antigen; MAGE-1; MZ2-E; MAGE1; MAGE1A

References & Citations :
Wang D, Wang J, Ding N, Li Y, Yang Y, Fang X, Zhao H. MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation. Biochem Biophys Res Commun. 2016 May 13;473(4):959-965. doi: 10.1016/j.bbrc.2016.03.161. Epub 2016 Apr 1. PMID: 27045082.

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