Name : Human CD206/MMR Protein
Product Source :
Recombinant Human CD206/MMR Protein is expressed from HEK293 with His tag at the C-terminus. It contains Leu19-Ala1389.[Accession | P22897-1]
Molecular Weight :
The protein has a predicted MW of 158.34 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human CD206 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human CD206 is greater than 95% as determined by SEC-HPLC.
Background :
Human mannose receptor 1 (hMRC1) is a transmembrane glycoprotein that belongs to the C-type lectin family and is expressed on the surface of most tissue macrophages. hMRC1 contributes to the binding and transmission of HIV-1 and is involved in the endocytic uptake of HIV-1 for subsequent antigen presentation.
Synonyms :
MMR; CD206; MRC1; CLEC13D; CLEC13DL; MRC1L1
References & Citations :
Saito H, Sukegawa S, Kao S, Strebel K. Human Mannose Receptor 1 Attenuates HIV-1 Infectivity in a Virus Isolate-Specific Manner. Viruses. 2023 Oct 6;15(10):2057. doi: 10.3390/v15102057. PMID: 37896833; PMCID: PMC10612104.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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