Name : Mouse Notch 4 Protein
Product Source :
Recombinant Mouse Notch 4 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Glu1042-Leu1441.[Accession | P31695]
Molecular Weight :
The protein has a predicted MW of 42.91 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in PB, 500mM NaCl, 10% Glycerol (pH 7.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse Notch 4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse Notch 4 is greater than 95% as determined by SEC-HPLC.
Background :
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells.
Synonyms :
Notch4; Int-3; Int3; Notch-4;
References & Citations :
(1) Ding LC, She L, Zheng DL, Huang QL, Wang JF, Zheng FF, Lu YG. Notch-4 contributes to the metastasis of salivary adenoid cystic carcinoma. Oncol Rep. 2010 Aug;24(2):363-8. doi: 10.3892/or_00000868. PMID: 20596622.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
Galectin-1/LGALS1 Protein
IRE1 Protein
Popular categories:
Death Receptor 4
FGF-2/bFGF