Name : Human PDGFD Protein
Product Source :
Recombinant Human PDGFD Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Arg19-Arg370.[Accession | Q9GZP0-1]
Molecular Weight :
The protein has a predicted MW of 41.82 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human PDGFD on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human PDGFD is greater than 95% as determined by SEC-HPLC.
Background :
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, including proliferation, migration, adhesion and tube formation, and thereby contributes to angiogenesis.
Synonyms :
PDGF-D; SCDGF-B; IEGF; SCDGFB
References & Citations :
Zhang J, Zhang H, Chen Y, Fu J, Lei Y, Sun J, Tang B. Platelet‑derived growth factor D promotes the angiogenic capacity of endothelial progenitor cells. Mol Med Rep. 2019 Jan;19(1):125-132. doi: 10.3892/mmr.2018.9692. Epub 2018 Nov 26. PMID: 30483778; PMCID: PMC6297765.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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