Name : Mouse PK-1/PROK1 Protein
Product Source :
Recombinant Mouse PK-1/PROK1 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ala20-Phe105.[Accession | Q14A28-1]
Molecular Weight :
The protein has a predicted MW of 36.4 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse PK-1/PROK1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
PK-1 (Ac10) is a baculovirus-encoded serine/threonine kinase,a pk-1 knockout AcMNPV failed to produce infectious progeny, while the pk-1 repair virus could rescue this defect.the kinase activity of PK-1 is essential in regulating viral propagation. Electron microscopy revealed that pk-1 deletion affected the formation of normal nucleocapsids.PK-1 appears to phosphorylate some viral or cellular proteins that are essential for DNA packaging to regulate nucleocapsid assembly.
Synonyms :
Prokineticin-1; EG-VEGF; Mambakine; PROK1
References & Citations :
(1) Liang C, Li M, Dai X, Zhao S, Hou Y, Zhang Y, Lan D, Wang Y, Chen X. Autographa californica multiple nucleopolyhedrovirus PK-1 is essential for nucleocapsid assembly. Virology. 2013 Sep 1;443(2):349-57. doi: 10.1016/j.virol.2013.05.025. Epub 2013 Jun 13. PMID: 23768784.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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