Name : Human RETN Protein

Product Source :
Recombinant Human RETN Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Ser17-Pro108.[Accession | Q9HD89-1]

Molecular Weight :
The protein has a predicted MW of 36.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC

Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human RETN on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human RETN is greater than 95% as determined by SEC-HPLC.

Background :
Resistin (RETN) is a hormone secreted by adipocytes, which plays an important role in glucose and lipid metabolism.The RETN gene is expressed in goat various analyzed tissues, and the results showed that the expression of RETN gene in lung tissue was higher than that in other analyzed tissues of goat (p <.01). Moreover, the expression level of RETN gene in the goat's intramuscular preadipocytes decreased first and then increased, and reached the highest on the fifth day, which was significantly higher than that of undifferentiated intramuscular preadipocytes.

Synonyms :
Resistin; ADSF; FIZZ3; HXCP1; RETN; RETN1; XCP1; ADSFMGC126609; FIZZ3MGC126603; RSTNXCP1

References & Citations :
(1) Zhang Y, Wang Y, Xu Q, Zhu J, Lin Y. Molecular and expression characteristics of resistin (RETN) and its effects on the differentiation of intramuscular preadipocyte in goat. Anim Biotechnol. 2021 Feb;32(1):113-120. doi: 10.1080/10495398.2019.1664564. Epub 2019 Sep 13. PMID: 31516062.

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