Name : Mouse S100A9/MRP14 Protein

Product Source :
Recombinant Mouse S100A9/MRP14 Protein is expressed from E.coli with His tag at the N-Terminus. It contains Ala2-Lys113.[Accession | P31725]

Molecular Weight :
The protein has a predicted MW of 14.1 kDa.The protein migrates to 29 kDa (dimer) &15 kDa (monomer) based on Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE

Formulation :
Supplied as 0.22μm filtered solution in PBS, 1mM DTT, 20% Glycerol (pH 7.5).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Mouse S100A9 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Background :
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism.

Synonyms :
S100-A9; Calgranulin-B; Calprotectin L1H subunit; MRP-14; p14; CAGB; MRP14

References & Citations :
(1) Wang S, Song R, Wang Z, Jing Z, Wang S, Ma J. S100A8/A9 in Inflammation. Front Immunol. 2018 Jun 11;9:1298. doi: 10.3389/fimmu.2018.01298. PMID: 29942307; PMCID: PMC6004386.

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