Name : Mouse SELL/CD62L Protein
Product Source :
Recombinant Mouse SELL/CD62L Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Trp39-Asn332.[Accession | P18337]
Molecular Weight :
The protein has a predicted MW of 34.2 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse SELL on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse SELL is greater than 95% as determined by SEC-HPLC.
Background :
L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that is expressed on most circulating leukocytes. Since its identification in 1983, L-selectin has been extensively characterized as a tethering/rolling receptor. There is now mounting evidence in the literature to suggest that L-selectin plays a role in regulating monocyte protrusion during transendothelial migration (TEM).
Synonyms :
L-selectin; LAM-1; LNHR; LYAM1; SELL; CD62L; LEU8; LSEL; PLNHR; TQ1
References & Citations :
(1) Ivetic A, Hoskins Green HL, Hart SJ. L-selectin: A Major Regulator of Leukocyte Adhesion, Migration and Signaling. Front Immunol. 2019 May 14;10:1068. doi: 10.3389/fimmu.2019.01068. PMID: 31139190; PMCID: PMC6527602.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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