Name : Human SMOC1 Protein
Product Source :
Recombinant Human SMOC1 Protein is expressed from HEK293 with His tag at the C-terminus. It contains His27-Val434.[Accession | Q9H4F8-1]
Molecular Weight :
The protein has a predicted MW of 46.43 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human SMOC1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
SPARC-related modular calcium binding 1 (SMOC1) represents a vital member of the SPARC matricellular protein family that regulates cell matrix interaction through binding to cell-surface receptors. SMOC1 silencing suppressed the Ang II‑induced myocardial fibrosis of mouse MFBs through affecting the BMP2/Smad signaling pathway.
Synonyms :
SMOC-1; OAS
References & Citations :
Wang Y, Wu X. SMOC1 silencing suppresses the angiotensin II-induced myocardial fibrosis of mouse myocardial fibroblasts via affecting the BMP2/Smad pathway. Oncol Lett. 2018 Sep;16(3):2903-2910. doi: 10.3892/ol.2018.8989. Epub 2018 Jun 19. PMID: 30127878; PMCID: PMC6096163.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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