Name : Human STAT4 Protein
Product Source :
Recombinant Human STAT4 Protein is expressed from Baculovirus-Insect Cells with His tag at the N-terminus. It contains Met1-Glu748.[Accession | Q14765]
Molecular Weight :
The protein has a predicted MW of 87.75 kDa same as Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 90% as determined by HPLC
Formulation :
Supplied as 0.22 μm filtered solution in 20mM Tris, 500mM NaCl, 20% glycerol, 0.5mM DTT (pH 7.5).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human STAT4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human STAT4 is greater than 90% as determined by SEC-HPLC.
Background :
Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the membrane, and then dimerized STAT4 translocates to the nucleus to regulate gene expression.
Synonyms :
STAT4; SLEB11
References & Citations :
Yang C, Mai H, Peng J, Zhou B, Hou J, Jiang D. STAT4: an immunoregulator contributing to diverse human diseases. Int J Biol Sci. 2020 Mar 5;16(9):1575-1585. doi: 10.7150/ijbs.41852. PMID: 32226303; PMCID: PMC7097918.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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