Name : Mouse TEM7R/PLXDC2 Protein

Product Source :
Recombinant Mouse TEM7R/PLXDC2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Glu31-Ala455.[Accession | Q9DC11]

Molecular Weight :
The protein has a predicted MW of 49.01 kDa. Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC

Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Mouse TEM7R on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse TEM7R is greater than 95% as determined by SEC-HPLC.

Background :
Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres.

Synonyms :
PLXDC2; TEM7R;

References & Citations :
(1) Kondkar AA, Sultan T, Almobarak FA, Kalantan H, Abu-Amero KK, Al-Obeidan SA. Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort. BMC Res Notes. 2018 Oct 16;11(1):733. doi: 10.1186/s13104-018-3848-x. PMID: 30326957; PMCID: PMC6192173.

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