Name : Human TREML2/TLT-2 Protein
Product Source :
Recombinant Human TREML2/TLT-2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gly19-Ser268.[Accession | Q5T2D2]
Molecular Weight :
The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 73-80 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human TREML2/TLT-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human TREML2/TLT-2 is greater than 95% as determined by SEC-HPLC.
Background :
As an important family member of triggering receptor expressed on myeloid cells (TREM), TREM-like transcript 2 gene (TREML2) locates on human chromosome 6p21.1, a newly-identified hot zone for AD susceptibility, and encodes atransmembrane immune receptor. Emerging evidence implied a potential role of TREML2 in the susceptibility and pathogenesis of AD.
Synonyms :
TLT-2; C6orf76; dJ238O23.1; FLJ13693; MGC149715; MGC149716; TREML2; UNQ6268/PRO20473
References & Citations :
(1) Wang SY, Gong PY, E Y, Zhang YD, Jiang T. The Role of TREML2 in Alzheimer’s Disease. J Alzheimers Dis. 2020;76(3):799-806. doi: 10.3233/JAD-200406. PMID: 32568208.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
IL-3 Proteincustom synthesis
ALK-7 Proteinsupplier
Popular categories:
Neuregulin-4 (NRG4)
Liver X Receptor