Name : Human TM4SF1 Protein-VLP
Product Source :
Recombinant Human TM4SF1 Protein-VLP is expressed from HEK293. It contains Met1-Cys202.[Accession | P30408]
Molecular Weight :
The target protein has a predicted MW of 21.64 kDa.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
SEC-HPLC The purity of Human TM4SF1 VLP is greater than 95% as determined by SEC-HPLC. ELISA Data Immobilized Human TM4SF1 VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-TM4SF1 Antibody, hFc Tag with the EC50 of 6.3ng/ml determined by ELISA.
Background :
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
Synonyms :
M3S1; TAAL6; H-L6; L6
References & Citations :
Yang JC, Zhang Y, He SJ, Li MM, Cai XL, Wang H, Xu LM, Cao J. TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. Sci Rep. 2017 Apr 3;7:45895. doi: 10.1038/srep45895. PMID: 28368050; PMCID: PMC5377454.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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