Name : Human TSPAN8 Protein
Product Source :
Recombinant Human TSPAN8 Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Lys110-Asn205.[Accession | P19075]
Molecular Weight :
The protein has a predicted MW of 37.30 kDa. Due to glycosylation, the protein migrates to 43-48 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human TSPAN8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human TSPAN8 is greater than 95% as determined by SEC-HPLC.
Background :
Tetraspanin 8 (TSPAN8) is a member of the tetraspanin superfamily that forms TSPAN8-mediated protein complexes by interacting with themselves and other various cellular signaling molecules.In physiological conditions, TSPAN8 plays a vital role in the regulation of biological functions, including leukocyte trafficking, angiogenesis and wound repair.
Synonyms :
Tetraspanin-8; Tetraspanin 8; Tspan-8; Tspan 8; TM4SF3; CO-029; TM4SF3; CO 029;
References & Citations :
Heo K, Lee S. TSPAN8 as a Novel Emerging Therapeutic Target in Cancer for Monoclonal Antibody Therapy. Biomolecules. 2020 Mar 3;10(3):388. doi: 10.3390/biom10030388. PMID: 32138170; PMCID: PMC7175299.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
VEGF164 Proteinsite
Profilin-4 Proteinsupplier
Popular categories:
Carbonic Anhydrase 8 ( CA-VIII)
IL-10R2