Name : Mouse BSPII Protein
Product Source :
Recombinant Mouse BSPII Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Phe17-Gln324.[Accession | Q61711]
Molecular Weight :
The protein has a predicted MW of 34.9 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse BSPII on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse BSPII is greater than 95% as determined by SEC-HPLC.
Background :
Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels.
Synonyms :
BNSP; BSP 2; BSP II; BSP; BSP-II; IBSP; SP II; SPII; SP-II
References & Citations :
(1) Adwan H, Bäuerle TJ, Berger MR. Downregulation of osteopontin and bone sialoprotein II is related to reduced colony formation and metastasis formation of MDA-MB-231 human breast cancer cells. Cancer Gene Ther. 2004 Feb;11(2):109-20. doi: 10.1038/sj.cgt.7700659. PMID: 14647232.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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